Endocrine Abstracts

Background/Aim: Diabetic ketoacidosis (DKA) is a life-threatening acute complication of diabetes. Our aim was to study the clinical features of DKA and precipitating factors responsible for DKA in diabetic patients.Methods: This is a retrospective cross-sectional descriptive study concerning all patients hospitalized in the Endocrinology Department for DKA between August 2021 and December 2021. Initial kalemia levels (k +) on presentation were determinat...

IntroductionThe thresholds of late night salivary cortisol (LNSC) vary widely among studies due to differences in assay methodologies and in control groups. We aimed to verify the analytical performance of the LNSC by electrochimiluminescence assay (ECLIA) and to establish cut-off values of LNSC for the screening of Cushing’s syndrome (CS).MethodsPatients with suspected CS underwent screening tests inclu...

IntroductionDermatological manifestations associated with diabetes affect approximately 30% of patients. Diabetic Bullosis is a rare complication of diabetes. It is a rare bullous dermatosis charecterised by the occurrence of bubbles on healthy skin with variable levels of cleavage.ObjectiveWe propose to study the epidemiological, clinical and evolutionary characteristics of Diabetic Bullosis in diabetic pati...

IntroductionUncontrolled hyperglycemia of diabetes is a common cause of renal failure and diabetic nephropathy, which is also called diabetic kidney disease (DKD). Despite improvements in the management of type 1 diabetes (T1D), progression of diabetic nephropathy remains unpredictable and associated with high morbidity and mortality. The objective of this study is to assess the prevalence and risk factors for diabetic kidney disease among adults-onset T...

Introduction: Serum sodium assay is one of the most commonly performed laboratory tests in a hospital setting. However, in some instances, the reported laboratory sodium results may not reflect the true actual values. Overcorrection of the serum sodium levels in pseudohyponatremia may cause serious complicationsCase Presentation: A 31-year-old woman was hospitalized in June 2022 in endocrinology department for asymptomatic hyponatremia. She was followed ...

IntroductionTriple-A syndrome, also known as Allgrove syndrome, is a rare autosomal recessive disorder. It is a multisystemic disease with an estimated prevalence of 1 per 1 000 000 individuals The 3 features of this syndrome are achalasia, adrenal insufficiency, and alacrima. Recently, dental impairment has been the subject of several case reports and reviews. However, this abnormality remains under-diagnosed.Purpose<p class="...

IntroductionSubclinical Cushing’s syndrome (SCS) is an endocrine disorder characterized by an autonomous cortisol secretion in patients bearing adrenal adenomas in the absence of specific signs of hypercortisolism. The cortisol excess is known to be associated with metabolic comorbidities such as obesity, hypertension, glucose intolerance, and dyslipidemia increasing the incidence of cardiovascular events. The objective of this study was to describe...

IntroductionType 1 diabetes (T1D), also known as juvenile diabetes, commonly occurs in young individuals. However, autoimmune diabetes may be diagnosed in the elderly, with different clinical and biological aspects. The aim of our study is to identify the prevalence of and risk factors for microvascular complications related to T1D diagnosed during adulthood.Patients and methodsA retrospective study, from 201...

BackgroundIt’s well known that smoking and diabetes are direct causes for serious health problems such as cancer, and atherosclerosis. It is suggested that smoking indirectly leads to atherosclerosis by influencing nutrient intakes as smokers tend to eat more fat and carbohydrates and less mono unsaturated fats and fiber than non-smokers. But no studies assessed the impact of tobacco on nutrition in diabetic patients.Aim<p...

IntroductionDiabetes mellitus is a serious metabolic disease, described by the World Health Organization as a global epidemic. An alarming increase in its prevalence among adults is observed in Tunisia as everywhere else in the world. Because type 2 diabetes preponderates among adults, few epidemiological studies focused on type 1 diabetes (T1D) that occurs during the adulthood. The aim of this study is to determine the prevalence of DT1 among Tunisian a...